Downregulation of ITGβ3 in colon adenocarcinoma reveals poor prognosis by affecting genome stability, cell cycle, and the tumor immune microenvironment

Downregulation of ITGβ3 in colon adenocarcinoma reveals poor prognosis by affecting genome stability, cell cycle, and the tumor immune microenvironment

IntroductionAbnormal expression of integrin subunit beta 3 (ITGβ3), a gene-encoding protein, is related to the occurrence and development of cancers; however, the biological role of ITGβ3 in colon adenocarcinoma (COAD) remains unclear.MethodsWe used the Cancer Genome Atlas database to obtain the cli...

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Bibliographic Details
Main Authors: Lei Zhao, Xiaoting Ma, Guangxin Li, Pengfei Zhao, Haishan Lin, Yingjie Ma, Huihui Li, Jing Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
Subjects:
ITGβ3
tumor invasion
prognosis
COAD
bioinformatics analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1047648/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.1047648/full

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