Extensive Alternative Splicing of KIR Transcripts

Extensive Alternative Splicing of KIR Transcripts

The killer-cell Ig-like receptors (KIR) form a multigene entity involved in modulating immune responses through interactions with MHC class I molecules. The complexity of the KIR cluster is reflected by, for instance, abundant levels of allelic polymorphism, gene copy number variation, and stochasti...

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Bibliographic Details
Main Authors: Jesse Bruijnesteijn, Marit K. H. van der Wiel, Nanine de Groot, Nel Otting, Annemiek J. M. de Vos-Rouweler, Neubury M. Lardy, Natasja G. de Groot, Ronald E. Bontrop
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-12-01
Series:Frontiers in Immunology
Subjects:
NK cell
killer cell immunoglobin-like receptor
KIR
human
rhesus macaque (Macaca mulatta)
alternative splicing
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02846/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02846/full

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