Quantitative modeling of multigenerational effects of chronic ionizing radiation using targeted and nontargeted effects

Abstract Stress response signals can propagate between cells damaged by targeted effects (TE) of ionizing radiation (e.g. energy depositions and ionizations in the nucleus) and undamaged “bystander” cells, sometimes over long distances. Their consequences, called non-targeted effects (NTE), can subs...

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Bibliographic Details
Main Authors: Igor Shuryak, David J. Brenner
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84156-2