Perspective on Quantitative Structure–Toxicity Relationship (QSTR) Models to Predict Hepatic Biotransformation of Xenobiotics

Perspective on Quantitative Structure–Toxicity Relationship (QSTR) Models to Predict Hepatic Biotransformation of Xenobiotics

Biotransformation refers to the metabolic conversion of endogenous and xenobiotic chemicals into more hydrophilic substances. Xenobiotic biotransformation is accomplished by a restricted number of enzymes with broad substrate specificities. The biotransformation of xenobiotics is catalyzed by variou...

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Bibliographic Details
Main Authors: Mansi Rai, Namuna Paudel, Mesevilhou Sakhrie, Donato Gemmati, Inshad Ali Khan, Veronica Tisato, Anurag Kanase, Armin Schulz, Ajay Vikram Singh
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Livers
Subjects:
hepatic biotransformation
metabolites
computational prediction
enzymes
xenobiotics
Online Access:https://www.mdpi.com/2673-4389/3/3/32

Internet

https://www.mdpi.com/2673-4389/3/3/32

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