Evaluation of the mechanical and release properties of lactose and microcrystalline cellulose and their binary mixtures as directly compressible excipients in paracetamol tablets.

Binary mixtures of microcrystalline cellulose MCC (A), and lactose (L) in ratios at 75:25, 50:50, and 25:75% respectively were prepared. The binary mixtures were subjected to microscopical analysis and density measurements. The mechanical properties of paracetamol tablets formulated with the above e...

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Bibliographic Details
Main Authors: Olufunke D Akin-Ajani, Oluwatoyin A Odeku, Ololade Olumakinde-Oni
Format: Article
Language:English
Published: International Pharmaceutical Excipients Council 2020-06-01
Series:Journal of Excipients and Food Chemicals
Online Access:https://jefc.scholasticahq.com/article/13506-evaluation-of-the-mechanical-and-release-properties-of-lactose-and-microcrystalline-cellulose-and-their-binary-mixtures-as-directly-compressible-excip