Recursive random forest algorithm for constructing multilayered hierarchical gene regulatory networks that govern biological pathways.

<h4>Background</h4>Present knowledge indicates a multilayered hierarchical gene regulatory network (ML-hGRN) often operates above a biological pathway. Although the ML-hGRN is very important for understanding how a pathway is regulated, there is almost no computational algorithm for dire...

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Bibliographic Details
Main Authors: Wenping Deng, Kui Zhang, Victor Busov, Hairong Wei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0171532&type=printable