Immunity to pathogens taught by specialized human dendritic cell subsets.

Dendritic cells (DC) are specialized antigen-presenting cells (APC) that have a key role in immune responses, because they bridge the innate and adaptive arms of the immune system. They mature upon recognition of pathogens and up-regulate MHC molecules and co-stimulatory receptors to activate antige...

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Bibliographic Details
Main Authors: Jens A. E. Geginat, Giulia eNizzoli, Moira eParoni, Stefano eMaglie, Paola eLarghi, Steve ePascolo, Sergio eAbrignani
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00527/full