Allograft inflammatory factor 1 is a regulator of transcytosis in M cells

M cells are intestinal epithelial cells that are specialized to transcytose antigens and bacteria from the intestinal lumen to antigen presenting cells on the other side. Here the authors show that the actin-binding protein Aif1 is highly expressed by intestinal M cells and regulates this transcytos...

Full description

Bibliographic Details
Main Authors: Sari Kishikawa, Shintaro Sato, Satoshi Kaneto, Shigeo Uchino, Shinichi Kohsaka, Seiji Nakamura, Hiroshi Kiyono
Format: Article
Language:English
Published: Nature Portfolio 2017-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14509