Allograft inflammatory factor 1 is a regulator of transcytosis in M cells
M cells are intestinal epithelial cells that are specialized to transcytose antigens and bacteria from the intestinal lumen to antigen presenting cells on the other side. Here the authors show that the actin-binding protein Aif1 is highly expressed by intestinal M cells and regulates this transcytos...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2017-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/ncomms14509 |
| _version_ | 1818421430551838720 |
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| author | Sari Kishikawa Shintaro Sato Satoshi Kaneto Shigeo Uchino Shinichi Kohsaka Seiji Nakamura Hiroshi Kiyono |
| author_facet | Sari Kishikawa Shintaro Sato Satoshi Kaneto Shigeo Uchino Shinichi Kohsaka Seiji Nakamura Hiroshi Kiyono |
| author_sort | Sari Kishikawa |
| collection | DOAJ |
| description | M cells are intestinal epithelial cells that are specialized to transcytose antigens and bacteria from the intestinal lumen to antigen presenting cells on the other side. Here the authors show that the actin-binding protein Aif1 is highly expressed by intestinal M cells and regulates this transcytosis. |
| first_indexed | 2024-12-14T13:10:14Z |
| format | Article |
| id | doaj.art-e17e8cc71f784c73972babb092522de6 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T13:10:14Z |
| publishDate | 2017-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-e17e8cc71f784c73972babb092522de62022-12-21T23:00:13ZengNature PortfolioNature Communications2041-17232017-02-018111010.1038/ncomms14509Allograft inflammatory factor 1 is a regulator of transcytosis in M cellsSari Kishikawa0Shintaro Sato1Satoshi Kaneto2Shigeo Uchino3Shinichi Kohsaka4Seiji Nakamura5Hiroshi Kiyono6Division of Mucosal Immunology, The Institute of Medical Science, The University of TokyoDivision of Mucosal Immunology, The Institute of Medical Science, The University of TokyoDivision of Mucosal Immunology, The Institute of Medical Science, The University of TokyoDepartment of Neurochemistry, National Institute of NeuroscienceDepartment of Neurochemistry, National Institute of NeuroscienceDivision of Maxillofacial Diagnostic and Surgical Sciences, Section of Oral and Maxillofacial Oncology, Faculty of Dental Science, Kyushu UniversityDivision of Mucosal Immunology, The Institute of Medical Science, The University of TokyoM cells are intestinal epithelial cells that are specialized to transcytose antigens and bacteria from the intestinal lumen to antigen presenting cells on the other side. Here the authors show that the actin-binding protein Aif1 is highly expressed by intestinal M cells and regulates this transcytosis.https://doi.org/10.1038/ncomms14509 |
| spellingShingle | Sari Kishikawa Shintaro Sato Satoshi Kaneto Shigeo Uchino Shinichi Kohsaka Seiji Nakamura Hiroshi Kiyono Allograft inflammatory factor 1 is a regulator of transcytosis in M cells Nature Communications |
| title | Allograft inflammatory factor 1 is a regulator of transcytosis in M cells |
| title_full | Allograft inflammatory factor 1 is a regulator of transcytosis in M cells |
| title_fullStr | Allograft inflammatory factor 1 is a regulator of transcytosis in M cells |
| title_full_unstemmed | Allograft inflammatory factor 1 is a regulator of transcytosis in M cells |
| title_short | Allograft inflammatory factor 1 is a regulator of transcytosis in M cells |
| title_sort | allograft inflammatory factor 1 is a regulator of transcytosis in m cells |
| url | https://doi.org/10.1038/ncomms14509 |
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