Practice of CYP450 genotyping and phenotyping in children in a real-life setting

Pharmacokinetics varies widely between children. Many factors play an important role in this variability, such as ontogeny, pharmacogenetics, gender, comorbidities, and drug-drug interactions. Significant work has already been done in adults to understand the impact of genetic polymorphisms on drug-...

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Bibliographic Details
Main Authors: Frédérique Rodieux, Youssef Daali, Victoria Rollason, Caroline F. Samer, Kuntheavy Ing Lorenzini
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1130100/full