HEPATIC SOD1 GENE EXPRESSION CHANGES IN THE NAFLD PATHOGENESIS IN OBESITY

Steatosis in the liver in obesity increases the work of mitochondria to utilize excess lipids. An overload of β-oxidation of fatty acids, the tricarboxylic acid cycle, and oxidative phosphorylation leads to a decrease in ATP and an increase in the formation of reactive oxygen species. Normally, mito...

Full description

Bibliographic Details
Main Authors: A. A. Komar, D. A. Shunkina (Skuratovsvkaia), M. A. Vulf, H. Q. Vu, N. M. Todosenko, P. A. Zatolokin, E. V. Kirienkova, N. D. Gazatova, L. S. Litvinova
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2021-10-01
Series:Медицинская иммунология
Subjects:
Online Access:https://www.mimmun.ru/mimmun/article/view/2282