HEPATIC SOD1 GENE EXPRESSION CHANGES IN THE NAFLD PATHOGENESIS IN OBESITY
Steatosis in the liver in obesity increases the work of mitochondria to utilize excess lipids. An overload of β-oxidation of fatty acids, the tricarboxylic acid cycle, and oxidative phosphorylation leads to a decrease in ATP and an increase in the formation of reactive oxygen species. Normally, mito...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | Russian |
Published: |
St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2021-10-01
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Series: | Медицинская иммунология |
Subjects: | |
Online Access: | https://www.mimmun.ru/mimmun/article/view/2282 |