HEPATIC SOD1 GENE EXPRESSION CHANGES IN THE NAFLD PATHOGENESIS IN OBESITY

HEPATIC SOD1 GENE EXPRESSION CHANGES IN THE NAFLD PATHOGENESIS IN OBESITY

Steatosis in the liver in obesity increases the work of mitochondria to utilize excess lipids. An overload of β-oxidation of fatty acids, the tricarboxylic acid cycle, and oxidative phosphorylation leads to a decrease in ATP and an increase in the formation of reactive oxygen species. Normally, mito...

Full description

Bibliographic Details
Main Authors: A. A. Komar, D. A. Shunkina (Skuratovsvkaia), M. A. Vulf, H. Q. Vu, N. M. Todosenko, P. A. Zatolokin, E. V. Kirienkova, N. D. Gazatova, L. S. Litvinova
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2021-10-01
Series:Медицинская иммунология
Subjects:
obesity
t2dm
superoxide dismutase
mtdna
liver
steatosis
Online Access:https://www.mimmun.ru/mimmun/article/view/2282

Similar Items

Similar Items