Iron Prevents Hypoxia-Associated Inflammation Through the Regulation of Nuclear Factor-κB in the Intestinal EpitheliumSummary

Iron Prevents Hypoxia-Associated Inflammation Through the Regulation of Nuclear Factor-κB in the Intestinal EpitheliumSummary

Background & Aims: Hypoxia-associated pathways influence the development of inflammatory bowel disease. Adaptive responses to hypoxia are mediated through hypoxia-inducible factors, which are regulated by iron-dependent hydroxylases. Signals reflecting oxygen tension and iron levels in enterocyt...

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Bibliographic Details
Main Authors: Simona Simmen, Jesus Cosin-Roger, Hassan Melhem, Nikolaos Maliachovas, Max Maane, Katharina Baebler, Bruce Weder, Chiaki Maeyashiki, Katharina Spanaus, Michael Scharl, Cheryl de Vallière, Jonas Zeitz, Stephan R. Vavricka, Martin Hausmann, Gerhard Rogler, Pedro A. Ruiz
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X18301528

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http://www.sciencedirect.com/science/article/pii/S2352345X18301528

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