Genetic disarray follows mutant KLF1-E325K expression in a congenital dyserythropoietic anemia patient
Congenital dyserythropoietic anemia type IV is caused by a heterozygous mutation, Glu325Lys (E325K), in the KLF1 transcription factor. Molecular characteristics of this disease have not been clarified, partly due to its rarity. We expanded erythroid cells from a patient’s peripheral blood and analyz...
| Glavni autori: | , , , , , , |
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| Format: | Članak |
| Jezik: | English |
| Izdano: |
Ferrata Storti Foundation
2019-12-01
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| Serija: | Haematologica |
| Online pristup: | https://haematologica.org/article/view/9161 |