Leishmania infantum Defective in Lipophosphoglycan Biosynthesis Interferes With Activation of Human Neutrophils

Visceral leishmaniasis (VL) is often associated with hematologic manifestations that may interfere with neutrophil response. Lipophosphoglycan (LPG) is a major molecule on the surface of Leishmania promastigotes, which has been associated with several aspects of the parasite–vector–host interplay. H...

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Main Authors: Graziele Quintela-Carvalho, Astrid Madeleine Calero Goicochea, Vanessa Mançur-Santos, Sayonara de Melo Viana, Yasmin da Silva Luz, Beatriz Rocha Simões Dias, Milena Lázaro-Souza, Martha Suarez, Camila Indiani de Oliveira, Elvira M. Saraiva, Cláudia I. Brodskyn, Patrícia T. Veras, Juliana P.B. de Menezes, Bruno B. Andrade, Jonilson Berlink Lima, Albert Descoteaux, Valéria M. Borges
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.788196/full