SIRT6 attenuates LPS‐induced inflammation and apoptosis of lung epithelial cells in acute lung injury through ACE2/STAT3/PIM1 signaling

Abstract Background Acute lung injury (ALI) is a severe and fatal respiratory disease. SIRT6 exerts pivotal activities in the process of lung diseases, but whether SIRT6 impacts ALI has not been covered. Methods Lentivirus recombinant expressing vector SIRT6 gene (Lent‐SIRT6) was constructed in mice...

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Bibliographic Details
Main Authors: Juan Yang, Xing Chen
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:Immunity, Inflammation and Disease
Subjects:
Online Access:https://doi.org/10.1002/iid3.809