The Restrictive Red Blood Cell Transfusion Strategy for Critically Injured Patients (RESTRIC) trial: a cluster-randomized, crossover, non-inferiority multicenter trial of restrictive transfusion in trauma

The Restrictive Red Blood Cell Transfusion Strategy for Critically Injured Patients (RESTRIC) trial: a cluster-randomized, crossover, non-inferiority multicenter trial of restrictive transfusion in trauma

Abstract Background The efficacies of fresh frozen plasma and coagulation factor transfusion have been widely evaluated in trauma-induced coagulopathy management during the acute post-injury phase. However, the efficacy of red blood cell transfusion has not been adequately investigated in patients w...

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Main Authors: Mineji Hayakawa, Takashi Tagami, Daisuke Kudo, Kota Ono, Makoto Aoki, Akira Endo, Tetsuya Yumoto, Yosuke Matsumura, Shiho Irino, Kazuhiko Sekine, Noritaka Ushio, Takayuki Ogura, Sho Nachi, Yuhei Irie, Katsura Hayakawa, Yusuke Ito, Yuko Okishio, Tomohiro Muronoi, Yoshinori Kosaki, Kaori Ito, Keita Nakatsutsumi, Yutaka Kondo, Taichiro Ueda, Hiroshi Fukuma, Yuichi Saisaka, Naoki Tominaga, Takeo Kurita, Fumihiko Nakayama, Tomotaka Shibata, Shigeki Kushimoto
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Journal of Intensive Care
Subjects:
Resuscitation
Red blood cell
Hemoglobin
Trauma
Transfusion
Online Access:https://doi.org/10.1186/s40560-023-00682-3

Internet

https://doi.org/10.1186/s40560-023-00682-3

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