An SPM-Enriched Marine Oil Supplement Shifted Microglia Polarization toward M2, Ameliorating Retinal Degeneration in <i>rd10</i> Mice

An SPM-Enriched Marine Oil Supplement Shifted Microglia Polarization toward M2, Ameliorating Retinal Degeneration in <i>rd10</i> Mice

Retinitis pigmentosa (RP) is the most common inherited retinal dystrophy causing progressive vision loss. It is accompanied by chronic and sustained inflammation, including M1 microglia activation. This study evaluated the effect of an essential fatty acid (EFA) supplement containing specialized pro...

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Bibliographic Details
Main Authors: Lorena Olivares-González, Sheyla Velasco, Idoia Gallego, Marina Esteban-Medina, Gustavo Puras, Carlos Loucera, Alicia Martínez-Romero, María Peña-Chilet, José Luis Pedraz, Regina Rodrigo
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Antioxidants
Subjects:
inherited retinal dystrophies
retinitis pigmentosa
inflammation
microglia
specialized pro-resolving mediators
oxidative stress
Online Access:https://www.mdpi.com/2076-3921/12/1/98

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https://www.mdpi.com/2076-3921/12/1/98

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