<i>Cymbopogon citratus</i> and Citral Overcome Doxorubicin Resistance in Cancer Cells via Modulating the Drug’s Metabolism, Toxicity, and Multidrug Transporters

<i>Cymbopogon citratus</i> and Citral Overcome Doxorubicin Resistance in Cancer Cells via Modulating the Drug’s Metabolism, Toxicity, and Multidrug Transporters

Multidrug resistance (MDR) is the major complex mechanism that causes the failure of chemotherapy, especially with drugs of natural origin such as doxorubicin (DOX). Intracellular drug accumulation and detoxification are also involved in cancer resistance by reducing the susceptibility of cancer cel...

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Bibliographic Details
Main Authors: Mohammed Hasan Mukhtar, Mahmoud Zaki El-Readi, Mohamed E. Elzubier, Sameer H. Fatani, Bassem Refaat, Usama Shaheen, Elshiekh Babiker Adam Khidir, Hesham Hamada Taha, Safaa Yehia Eid
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Molecules
Subjects:
<i>Cymbopogon citratus</i>
essential oil
lemon grass
multidrug resistance
doxorubicin
citral
Online Access:https://www.mdpi.com/1420-3049/28/8/3415

Internet

https://www.mdpi.com/1420-3049/28/8/3415

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