Novel methods for genotype imputation to whole-genome sequence and a simple linear model to predict imputation accuracy

Novel methods for genotype imputation to whole-genome sequence and a simple linear model to predict imputation accuracy

Abstract Background Accurate imputation plays a major role in genomic studies of livestock industries, where the number of genotyped or sequenced animals is limited by costs. This study explored methods to create an ideal reference population for imputation to Next Generation Sequencing data in catt...

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Bibliographic Details
Main Authors: Steven G. Larmer, Mehdi Sargolzaei, Luiz F. Brito, Ricardo V. Ventura, Flávio S. Schenkel
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Genetics
Subjects:
Cattle genomics
Genomic clustering
Genotype imputation
Sequencing data
Online Access:http://link.springer.com/article/10.1186/s12863-017-0588-1

Internet

http://link.springer.com/article/10.1186/s12863-017-0588-1

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