Sperm associated antigen 9 promotes oncogenic KSHV-encoded interferon regulatory factor-induced cellular transformation and angiogenesis by activating the JNK/VEGFA pathway.

Sperm associated antigen 9 promotes oncogenic KSHV-encoded interferon regulatory factor-induced cellular transformation and angiogenesis by activating the JNK/VEGFA pathway.

Kaposi's sarcoma (KS), caused by Kaposi's sarcoma-associated herpesvirus (KSHV), is a highly angioproliferative disseminated tumor of endothelial cells commonly found in AIDS patients. We have recently shown that KSHV-encoded viral interferon regulatory factor 1 (vIRF1) mediates KSHV-induc...

Full description

Bibliographic Details
Main Authors: Wan Li, Fei Wang, Jiale Shi, Qi Feng, Yuheng Chen, Xiaoyu Qi, Cong Wang, Hongmei Lu, Zhongmou Lu, Xuemei Jia, Qin Yan, Shou-Jiang Gao, Chun Lu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008730

Internet

https://doi.org/10.1371/journal.ppat.1008730

Similar Items