Importance of Heparan Sulfate Proteoglycans in Pancreatic Islets and β-Cells
β-cells in the islets of Langerhans of the pancreas secrete insulin in response to the glucose concentration in the blood. When these pancreatic β-cells are damaged, diabetes develops through glucose intolerance caused by insufficient insulin secretion. High molecular weight polysaccharides, such as...
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Format: | Article |
Language: | English |
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MDPI AG
2022-10-01
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Series: | International Journal of Molecular Sciences |
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Online Access: | https://www.mdpi.com/1422-0067/23/20/12082 |