Enhanced Insulin Production From Porcine Islets: More Insulin, Less Islets

Clinical pancreatic islet xenotransplantation will most probably rely on genetically modified pigs as donors. Several lines of transgenic pigs carrying one and more often, multiple modifications already exist. The vast majority of these modifications aim to mitigate the host immune response by suppr...

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Bibliographic Details
Main Authors: Nizar I. Mourad, Pierre Gianello
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Transplant International
Subjects:
Online Access:https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13954/full