Marine-Inspired Bis-indoles Possessing Antiproliferative Activity against Breast Cancer; Design, Synthesis, and Biological Evaluation

Marine-Inspired Bis-indoles Possessing Antiproliferative Activity against Breast Cancer; Design, Synthesis, and Biological Evaluation

Diverse indoles and bis-indoles extracted from marine sources have been identified as promising anticancer leads. Herein, we designed and synthesized novel bis-indole series <b>7a</b>–<b>f</b> and <b>9a</b>–<b>h</b> as Topsentin and Nortopsentin analog...

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Bibliographic Details
Main Authors: Wagdy M. Eldehna, Ghada S. Hassan, Sara T. Al-Rashood, Hamad M. Alkahtani, Abdulrahman A. Almehizia, Ghada H. Al-Ansary
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Marine Drugs
Subjects:
marine-inspired
breast cancer
bis-indoles
synthesis
apoptosis
Online Access:https://www.mdpi.com/1660-3397/18/4/190

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https://www.mdpi.com/1660-3397/18/4/190

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