Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis

Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis

Gastric cancer (GC) is the third cause of cancer-related mortality worldwide. Nevertheless, because GC screening programs are not cost-effective, most patients receive diagnosis in the advanced stages, when surgical options are limited. Peritoneal dissemination occurs in approximately one-third of p...

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Bibliographic Details
Main Authors: Cristina Di Giorgio, Silvia Marchianò, Elisabetta Marino, Michele Biagioli, Rosalinda Roselli, Martina Bordoni, Rachele Bellini, Ginevra Urbani, Angela Zampella, Eleonora Distrutti, Annibale Donini, Luigina Graziosi, Stefano Fiorucci
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
gastric cancer (GC)
metastases
peritoneal carcinomatosis (PC)
trascriptome analysis
biomarker
LIF/LIFR axis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.939969/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.939969/full

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