Maternal and paternal obesity differentially reprogram the ovarian mitochondrial biogenesis of F1 female rats

Abstract Obesity has harmful consequences on reproductive outcomes and the rapid increase in obesity is assumed to be influenced by epigenetics and trans-generation effects. Our study aimed to explore the effect of maternal and/or paternal obesity on the ovarian tissues of the first-generation femal...

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Bibliographic Details
Main Authors: Amina G. Ramadan, Wafaa M. Abdel-Rehim, Rasha A. El-Tahan, Samar S. Elblehi, Maher A. Kamel, Sara A. Shaker
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-42468-5