Molecular tracking devices quantify antigen distribution and archiving in the murine lymph node

Molecular tracking devices quantify antigen distribution and archiving in the murine lymph node

The detection of foreign antigens in vivo has relied on fluorescent conjugation or indirect read-outs such as antigen presentation. In our studies, we found that these widely used techniques had several technical limitations that have precluded a complete picture of antigen trafficking or retention...

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Bibliographic Details
Main Authors: Shannon M Walsh, Ryan M Sheridan, Erin D Lucas, Thu A Doan, Brian C Ware, Johnathon Schafer, Rui Fu, Matthew A Burchill, Jay R Hesselberth, Beth Ann Jiron Tamburini
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-04-01
Series:eLife
Subjects:
single-cell mRNA sequencing
lymph node
antigen processing
antigen archiving
lymphatic endothelial cell
dendritic cell
Online Access:https://elifesciences.org/articles/62781

Internet

https://elifesciences.org/articles/62781

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