Baricitinib attenuates pulmonary fibrosis in scleroderma mice by regulating macrophage polarization

Baricitinib attenuates pulmonary fibrosis in scleroderma mice by regulating macrophage polarization

Objective To determine whether baricitinib regulates macrophage polarization through Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) signaling pathway to reduce the severity of pulmonary fibrosis in mice with scleroderma. Methods Thirty 8-week-old female C57BL/6 mic...

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Bibliographic Details
Main Authors: WANG Dandan, XU Lulu, ZHANG Jie
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2024-01-01
Series:陆军军医大学学报
Subjects:
scleroderma
interstitial lung disease
baricitinib
jak2/stat3
macrophages
Online Access:http://aammt.tmmu.edu.cn/html/202306114.htm

Internet

http://aammt.tmmu.edu.cn/html/202306114.htm

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