Exceptional diversity, maintenance of polymorphism, and recent directional selection on the APL1 malaria resistance genes of Anopheles gambiae.
The three-gene APL1 locus encodes essential components of the mosquito immune defense against malaria parasites. APL1 was originally identified because it lies within a mapped QTL conferring the vector mosquito Anopheles gambiae natural resistance to the human malaria parasite, Plasmodium falciparum...
| Автори: | , , , , , , , , |
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| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Public Library of Science (PLoS)
2011-03-01
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| Серія: | PLoS Biology |
| Онлайн доступ: | http://europepmc.org/articles/PMC3050937?pdf=render |