The Janus-faced role of TRPM2-S in retroperitoneal liposarcoma via increasing ROS levels

The Janus-faced role of TRPM2-S in retroperitoneal liposarcoma via increasing ROS levels

Abstract Background Retroperitoneal liposarcoma (RPLS) is a specific soft tissue sarcoma with a high recurrence rate. The short isoform of transient receptor potential cation channel subfamily M member 2 (TRPM2-S) plays an important role in the regulation of reactive oxygen species (ROS). However, t...

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Bibliographic Details
Main Authors: Xiangji Li, Fanqin Bu, Shixiang Ma, Ferdinando Cananzi, Yu Zhao, Mengmeng Xiao, Li Min, Chenghua Luo
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Cell Communication and Signaling
Subjects:
TRPM2-S
Retroperitoneal liposarcoma
ROS
Dual effects
Prognosis
Online Access:https://doi.org/10.1186/s12964-022-00873-9

Internet

https://doi.org/10.1186/s12964-022-00873-9

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