Parathyroid hormone stimulates bone regeneration in an atrophic non-union model in aged mice

Parathyroid hormone stimulates bone regeneration in an atrophic non-union model in aged mice

Abstract Background Non-union formation still represents a major burden in trauma and orthopedic surgery. Moreover, aged patients are at an increased risk for bone healing failure. Parathyroid hormone (PTH) has been shown to accelerate fracture healing in young adult animals. However, there is no in...

Full description

Bibliographic Details
Main Authors: Maximilian M. Menger, Anne L. Tobias, David Bauer, Michelle Bleimehl, Claudia Scheuer, Michael D. Menger, Tina Histing, Matthias W. Laschke
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Translational Medicine
Subjects:
Non-union
Parathyroid hormone
Segmental defect
Bone regeneration
Fracture healing
Angiogenesis
Online Access:https://doi.org/10.1186/s12967-023-04661-y

Internet

https://doi.org/10.1186/s12967-023-04661-y

Similar Items