Mechanism and Protective Effect of Smilax glabra Roxb on the Treatment of Heart Failure via Network Pharmacology Analysis and Vitro Verification

Mechanism and Protective Effect of Smilax glabra Roxb on the Treatment of Heart Failure via Network Pharmacology Analysis and Vitro Verification

Smilax glabra Roxb (SGR) has been widely applied alone or in combination with other Chinese herbs in heart failure (HF), but its mechanism and protective effect have not been investigated. We aimed to explore the mechanism and protective effect of SGR on the treatment of HF. Network pharmacology ana...

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Bibliographic Details
Main Authors: Yingxin Long, Zunjiang Li, Chunxia Huang, Zhongyu Lu, Kuncheng Qiu, Meixing He, Zhijian Fang, Banghan Ding, Xiaohong Yuan, Wei Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Pharmacology
Subjects:
Smilax glabra Roxb
heart failure
mitochondrial dysfunction
network pharmacology analysis
UHPLC-LTQ-Orbitrap-MSn method
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.868680/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.868680/full

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