Glioblastoma may evade immune surveillance through primary cilia-dependent signaling in an IL-6 dependent manner

Glioblastoma may evade immune surveillance through primary cilia-dependent signaling in an IL-6 dependent manner

Glioblastoma is the most common, malignant primary brain tumor in adults and remains universally fatal. While immunotherapy has vastly improved the treatment of several solid cancers, efficacy in glioblastoma is limited. These challenges are due in part to the propensity of glioblastoma to recruit t...

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Bibliographic Details
Main Authors: Maxwell T. Laws, Erin N. Walker, Francesca M. Cozzi, Leonel Ampie, Mi-Yeon Jung, Eric C. Burton, Desmond A. Brown
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Oncology
Subjects:
glioblastoma
extracellular vesicles
primary cilia
glioblastoma-mediated immunosuppression
IL-6
CCRK
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1279923/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2023.1279923/full

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