Fatty acid nitroalkenes – Multi-target agents for the treatment of sickle cell disease

Fatty acid nitroalkenes – Multi-target agents for the treatment of sickle cell disease

Sickle cell disease (SCD) is a hereditary hematological disease with high morbidity and mortality rates worldwide. Despite being monogenic, SCD patients display a plethora of disease-associated complications including anemia, oxidative stress, sterile inflammation, vaso-occlusive crisis-related pain...

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Bibliographic Details
Main Authors: Fabliha A. Chowdhury, Nicole Colussi, Malini Sharma, Katherine C. Wood, Julia Z. Xu, Bruce A. Freeman, Francisco J. Schopfer, Adam C. Straub
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Redox Biology
Subjects:
Nitro-fatty acid
Sickle cell anemia
Oxidative stress
Inflammation
Multi-organ pathophysiology
Vascular
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723003427

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http://www.sciencedirect.com/science/article/pii/S2213231723003427

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