Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment

Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment

Bone marrow mesenchymal lineage cells are a heterogeneous cell population involved in bone homeostasis and diseases such as osteoporosis. While it is long postulated that they originate from mesenchymal stem cells, the true identity of progenitors and their in vivo bifurcated differentiation routes...

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Bibliographic Details
Main Authors: Leilei Zhong, Lutian Yao, Robert J Tower, Yulong Wei, Zhen Miao, Jihwan Park, Rojesh Shrestha, Luqiang Wang, Wei Yu, Nicholas Holdreith, Xiaobin Huang, Yejia Zhang, Wei Tong, Yanqing Gong, Jaimo Ahn, Katalin Susztak, Nathanial Dyment, Mingyao Li, Fanxin Long, Chider Chen, Patrick Seale, Ling Qin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-04-01
Series:eLife
Subjects:
adipocyte
bone marrow mesenchymal stem cells
osteoblast
blood vessel
single cell RNA-seq
Online Access:https://elifesciences.org/articles/54695

Internet

https://elifesciences.org/articles/54695

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