SPINK4 promotes colorectal cancer cell proliferation and inhibits ferroptosis

SPINK4 promotes colorectal cancer cell proliferation and inhibits ferroptosis

Abstract Background Little is known about the role of serine peptidase inhibitor Kazal type 4 (SPINK4) in colorectal cancer (CRC) and ferroptosis. Therefore, this study aimed to determine the effect of SPINK4 on CRC pathogenesis and ferroptosis. Methods SPINK4 expression was analyzed in public datas...

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Bibliographic Details
Main Authors: Bang-li Hu, Yi-xin Yin, Ke-zhi Li, Si-qi Li, Zhao Li
Format: Article
Language:English
Published: BMC 2023-04-01
Series:BMC Gastroenterology
Subjects:
Colorectal cancer
SPINK4
Ferroptosis
Mouse model
Online Access:https://doi.org/10.1186/s12876-023-02734-2

Internet

https://doi.org/10.1186/s12876-023-02734-2

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