Proteome-wide 3D structure prediction provides insights into the ancestral metabolism of ancient archaea and bacteria

Proteome-wide 3D structure prediction provides insights into the ancestral metabolism of ancient archaea and bacteria

Previous studies have reconstructed ancestral metabolism using sequence-based approaches. This study uses a high-throughput version of AlphaFold2 to compare proteome-wide 3D structure predictions of two representative strains of ancient archaea and bacteria.

Bibliographic Details
Main Authors: Weishu Zhao, Bozitao Zhong, Lirong Zheng, Pan Tan, Yinzhao Wang, Hao Leng, Nicolas de Souza, Zhuo Liu, Liang Hong, Xiang Xiao
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35523-8

Internet

https://doi.org/10.1038/s41467-022-35523-8

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