Mechanisms of NK cell-macrophage Bacillus anthracis crosstalk: a balance between stimulation by spores and differential disruption by toxins.

NK cells are important immune effectors for preventing microbial invasion and dissemination, through natural cytotoxicity and cytokine secretion. Bacillus anthracis spores can efficiently drive IFN-γ production by NK cells. The present study provides insights into the mechanisms of cytokine and cell...

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Bibliographic Details
Main Authors: Maria Klezovich-Bénard, Jean-Philippe Corre, Hélène Jusforgues-Saklani, Daniel Fiole, Nick Burjek, Jean-Nicolas Tournier, Pierre L Goossens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3257302?pdf=render