IgE regulates the expression of smMLCK in human airway smooth muscle cells.

Previous studies have shown that enhanced accumulation of contractile proteins such as smooth muscle myosin light chain kinase (smMLCK) plays a major role in human airway smooth muscle cells (HASM) cell hypercontractility and hypertrophy. Furthermore, serum IgE levels play an important role in smoot...

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Bibliographic Details
Main Authors: Jyoti Balhara, Naresh Singh Redhu, Lianyu Shan, Abdelilah S Gounni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3983085?pdf=render