stormTB: a web-based simulator of a murine minimal-PBPK model for anti-tuberculosis treatments

IntroductionTuberculosis (TB) poses a significant threat to global health, with millions of new infections and approximately one million deaths annually. Various modeling efforts have emerged, offering tailored data-driven and physiologically-based solutions for novel and historical compounds. Howev...

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Bibliographic Details
Main Authors: Roberto Visintainer, Anna Fochesato, Daniele Boaretti, Stefano Giampiccolo, Shayne Watson, Micha Levi, Federico Reali, Luca Marchetti
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1462193/full