Review: Mitochondrial Defects in Breast Cancer
Mitochondria play important roles in cellular energy metabolism, free radical generation, and apoptosis. Mitochondrial DNA has been proposed to be involved in carcinogenesis because of its high susceptibility to mutations and limited repair mechanisms in comparison to nuclear DNA. Breast cancer is t...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2008-01-01
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Series: | Clinical Medicine Insights: Oncology |
Online Access: | https://doi.org/10.4137/CMO.S524 |