Combination of ferric ammonium citrate with cytokines involved in apoptosis and insulin secretion of human pancreatic beta cells related to diabetes in thalassemia
Background Diabetes mellitus (DM) is a common complication found in β-thalassemia patients. The mechanism of DM in β-thalassemia patients is still unclear, but it could be from an iron overload and increase of some cytokines, such as interleukin1-β (IL-1β) and tumor necrosis factor-α (TNF-α). The ob...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2020-06-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/9298.pdf |