The roles of FGF21 and GDF15 in mediating the mitochondrial integrated stress response

Various models of mitochondrial stress result in induction of the stress-responsive cytokines fibroblast growth factor 21 (FGF21) and growth differentiation factor 15 (GDF15). This is an adaptive mechanism downstream of the mitochondrial integrated stress response frequently associated with improvem...

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Bibliographic Details
Main Authors: Jayashree Jena, Luis Miguel García-Peña, Renata O. Pereira
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1264530/full