Dynamical analysis of a delayed p53 oscillator model with p53-Mdm2 positive feedback
The p53 oscillator is an essential cell fate controller after DNA damage. In general, the delayed p53-Mdm2 negative feedback loop is thought to be the foundational structure responsible for p53 oscillations. However, it is experimentally found that Mdm2 also has a positive effect on p53. Therefore,...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2022-09-01
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| Series: | Results in Physics |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211379722004995 |