Engineering Saccharomyces cerevisiae for targeted hydrolysis and fermentation of glucuronoxylan through CRISPR/Cas9 genome editing

Engineering Saccharomyces cerevisiae for targeted hydrolysis and fermentation of glucuronoxylan through CRISPR/Cas9 genome editing

Abstract Background The abundance of glucuronoxylan (GX) in agricultural and forestry residual side streams positions it as a promising feedstock for microbial conversion into valuable compounds. By engineering strains of the widely employed cell factory Saccharomyces cerevisiae with the ability to...

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Bibliographic Details
Main Authors: Jonas L. Ravn, João H.C. Manfrão-Netto, Jana B. Schaubeder, Luca Torello Pianale, Stefan Spirk, Iván F. Ciklic, Cecilia Geijer
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Microbial Cell Factories
Subjects:
Yeast
Xylan
Xylanase
α-glucuronidase
Metabolic engineering
Co-culture
Online Access:https://doi.org/10.1186/s12934-024-02361-w

Internet

https://doi.org/10.1186/s12934-024-02361-w

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