Downregulation of <i>ORP3</i> Correlates with Reduced Survival of Colon Cancer Patients with Advanced Nodal Metastasis and of Female Patients with Grade 3 Colon Cancer

Genome instability is an essential hallmark in tumor development, including colorectal cancer. We have recently identified the oxysterol binding protein-related protein 3 (ORP3), also known as oxysterol binding protein-like 3 (OSBPL3), as a novel ploidy-control gene, whose knock-out leads to aneuplo...

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Bibliographic Details
Main Authors: Pengfei Xu, Julia Richter, Annette Blatz, Fabian Gärtner, Roland Alberts, Anca Azoitei, Wycliffe Arika Makori, Sabine Meessen, Uwe Knippschild, Cagatay Günes
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/16/5894