Deficiency of two-pore segment channel 2 contributes to systemic lupus erythematosus via regulation of apoptosis and cell cycle

Abstract. Background:. Systemic lupus erythematosus (SLE) is a complex autoimmune disease, and the mechanism of SLE is yet to be fully elucidated. The aim of this study was to explore the role of two-pore segment channel 2 (TPCN2) in SLE pathogenesis. Methods:. Quantitative reverse transcription pol...

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Bibliographic Details
Main Authors: Keke Li, Jingkai Xu, Ke Xue, Ruixing Yu, Chengxu Li, Wenmin Fei, Xiaoli Ning, Yang Han, Ziyi Wang, Jun Shu, Yong Cui, Lishao Guo
Format: Article
Language:English
Published: Wolters Kluwer 2022-02-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000001893