The identification of a novel shared therapeutic target and drug across all insulin-sensitive tissues under insulin resistance

The identification of a novel shared therapeutic target and drug across all insulin-sensitive tissues under insulin resistance

BackgroundTo identify key and shared insulin resistance (IR) molecular signatures across all insulin-sensitive tissues (ISTs), and their potential targeted drugs.MethodsThree datasets from Gene Expression Omnibus (GEO) were acquired, in which the ISTs (fat, muscle, and liver) were from the same indi...

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Bibliographic Details
Main Authors: Jinyuan Xu, Lilin Zhu, Jie Xu, Kailong Lin, Juan Wang, Yan-long Bi, Guo-Tong Xu, Haibin Tian, Furong Gao, Caixia Jin, Lixia Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Nutrition
Subjects:
bioinformatics
insulin resistance
ubiquitin D
promethazine
insulin-sensitive tissues
Online Access:https://www.frontiersin.org/articles/10.3389/fnut.2024.1381779/full

Internet

https://www.frontiersin.org/articles/10.3389/fnut.2024.1381779/full

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