Modulation of Type 5 Metabotropic Glutamate Receptor-Mediated Intracellular Calcium Mobilization by Regulator of G Protein Signaling 4 (RGS4) in Cultured Astrocytes

Acting as GTPase activating proteins promoting the silencing of activated G-proteins, regulators of G protein signaling (RGSs) are generally considered negative modulators of cell signaling. In the CNS, the expression of RGS4 is altered in diverse pathologies and its upregulation was reported in ast...

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Bibliographic Details
Main Authors: Pauline Beckers, Pierre J. Doyen, Emmanuel Hermans
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/13/4/291